Interactive Methods Calculators

Six calculators for common RWE/HEOR quantities. All computation runs in your browser — no data is transmitted. Each result links to the full methods entry in the Repository.

Educational tools only. These calculators are not clinical, regulatory, or submission-ready software. Verify all outputs against primary references before use in any formal analysis.

E-value (Sensitivity Analysis)

How strong must unmeasured confounding be to explain away the association?

NNT / NNH

Number needed to treat or harm, from risks or from a relative measure.

PDC — Proportion of Days Covered

Overlap-adjusted medication adherence over an observation window.

Post-test Probability (Likelihood Ratios)

Bayes' rule in odds form: convert pre-test probability with LR+ and LR−.

Sample Size — Two Proportions

Normal approximation (Fleiss). Label as an approximation; verify with exact methods for submissions.

OR → RR Converter (Zhang-Yu)

Converts an odds ratio to a risk ratio when the outcome is common. Warns when baseline risk is large.